Evidence-Backed Advanced Diagnostics—Used Wisely
- Andres Jimenez
- Oct 13
- 2 min read

“Advanced testing is powerful when it’s purposeful. The goal isn’t to order more tests—it’s to identify a small group that truly benefits, while sparing everyone else the anxiety, time away from work, and downstream procedures that come from incidental findings. Risk-first protocols, clear thresholds, and primary-care alignment keep employees safe and operations smooth. We measure value not by the number of tests run, but by better decisions made sooner.” Dr. Andres Jimenez, Board-Certified in Public Health & Prevention, and Clinical Informatics. Founder & CEO of HealthPrevent360
Early detection beyond guidelines can be valuable—if it’s disciplined. Many direct-to-consumer offerings cast a wide net by age and gender, which can flood clinics with false alarms and saddle employees with extra appointments, biopsies, and time off. A responsible employer strategy pairs risk stratification with evidence-based escalation and harm minimization.
How to use advanced diagnostics without the backlash
Start with risk, not the menu. Use validated cardio-metabolic, family-history, and symptom/risk indices to determine who merits deeper evaluation.
Define thresholds up front. Make the “why” and “when” for escalation transparent (e.g., a specific risk score or clinical trigger).
Limit incidental harm. Prefer tests with strong positive predictive value in the targeted group; set conservative rules for follow-up imaging or invasive workups.
Keep PCPs in the loop. Summaries should be concise, clinically actionable, and avoid “diagnosis shopping.”
Track operational impact. Monitor avoided escalations, time away from work, and net benefit of findings that changed care.
Incidental findings are common—an American Journal of Roentgenology review estimates ~15–30% of diagnostic imaging and 20–40% of CT exams contain at least one incidental finding, many of which lead to additional workups without improving outcomes. American Journal of Roentgenology
Bottom line: Advanced diagnostics add value when they’re selective, explainable, and measured—not when they’re marketed to everyone.
How HP360 supports employers—advanced, but appropriate
We emphasize appropriateness and employee safety while preserving productivity.
Risk-first protocols and clear escalation thresholds
Evidence-based test selection to reduce false alarms
PCP-aligned summaries and next-step guidance
Monitoring of downstream utilization and time off
Outcome tracking (findings that change care vs. noise)
About Dr. Jimenez
Board-certified physician, triple Ivy League–trained innovator leading the nation’s first prevention-only clinic. Dr. Jimenez has built physician-led technology adopted by 3,000+ hospitals and clinics, guided companies through acquisition and IPO, and serves as Assistant Clinical Professor (Environmental & Public Health) at Mount Sinai School of Medicine in NY. At HealthPrevent360, he applies clinical informatics and prevention science to help individuals anticipate risk, prevent and early-detect disease. The clinic’s prevention engine has analyzed hundreds of thousands of clinical pages and supports thousands of patients.
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