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Evidence-Backed Advanced Diagnostics—Used Wisely

  • Andres Jimenez
  • Oct 13
  • 2 min read

Andres Jimenez MD MSED MBA MS
Andres Jimenez MD MSED MBA MS

“Advanced testing is powerful when it’s purposeful. The goal isn’t to order more tests—it’s to identify a small group that truly benefits, while sparing everyone else the anxiety, time away from work, and downstream procedures that come from incidental findings. Risk-first protocols, clear thresholds, and primary-care alignment keep employees safe and operations smooth. We measure value not by the number of tests run, but by better decisions made sooner.” Dr. Andres Jimenez, Board-Certified in Public Health & Prevention, and Clinical Informatics. Founder & CEO of HealthPrevent360


Early detection beyond guidelines can be valuable—if it’s disciplined. Many direct-to-consumer offerings cast a wide net by age and gender, which can flood clinics with false alarms and saddle employees with extra appointments, biopsies, and time off. A responsible employer strategy pairs risk stratification with evidence-based escalation and harm minimization.


How to use advanced diagnostics without the backlash


  • Start with risk, not the menu. Use validated cardio-metabolic, family-history, and symptom/risk indices to determine who merits deeper evaluation.

  • Define thresholds up front. Make the “why” and “when” for escalation transparent (e.g., a specific risk score or clinical trigger).

  • Limit incidental harm. Prefer tests with strong positive predictive value in the targeted group; set conservative rules for follow-up imaging or invasive workups.

  • Keep PCPs in the loop. Summaries should be concise, clinically actionable, and avoid “diagnosis shopping.”

  • Track operational impact. Monitor avoided escalations, time away from work, and net benefit of findings that changed care.


Incidental findings are common—an American Journal of Roentgenology review estimates ~15–30% of diagnostic imaging and 20–40% of CT exams contain at least one incidental finding, many of which lead to additional workups without improving outcomes. American Journal of Roentgenology

Bottom line: Advanced diagnostics add value when they’re selective, explainable, and measured—not when they’re marketed to everyone.


How HP360 supports employers—advanced, but appropriate

We emphasize appropriateness and employee safety while preserving productivity.

  • Risk-first protocols and clear escalation thresholds

  • Evidence-based test selection to reduce false alarms

  • PCP-aligned summaries and next-step guidance

  • Monitoring of downstream utilization and time off

  • Outcome tracking (findings that change care vs. noise)


About Dr. Jimenez

Board-certified physician, triple Ivy League–trained innovator leading the nation’s first prevention-only clinic. Dr. Jimenez has built physician-led technology adopted by 3,000+ hospitals and clinics, guided companies through acquisition and IPO, and serves as Assistant Clinical Professor (Environmental & Public Health) at Mount Sinai School of Medicine in NY. At HealthPrevent360, he applies clinical informatics and prevention science to help individuals anticipate risk, prevent and early-detect disease. The clinic’s prevention engine has analyzed hundreds of thousands of clinical pages and supports thousands of patients.

 
 
 

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